NAD+ Dosing Calculator & Reconstitution Guide
A coenzyme researched for cellular energy and longevity.
NAD+ is a research peptide. A coenzyme researched for cellular energy and longevity. To dose it, reconstitute the vial (for example 500 mg in 5 mL of bacteriostatic water for 100 mg/mL), then divide your target dose by that concentration to find the units to draw.
- Category
- research peptide
- Dose unit
- mg
- Commonly reported range
- 50-100 mg
- Typical concentration
- 100 mg/mL
Use the Keel dose calculator to enter your numbers and see the exact units to draw, or use the built-in calculator further down this page.
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular energy metabolism. It is studied for its potential roles in mitochondrial function, DNA repair, and healthy aging. Research doses are relatively large and are typically expressed in milligrams. Also known as nicotinamide adenine dinucleotide, NAD.
How many units is each NAD+ dose?
| Dose | Volume to draw | Units (U-100) |
|---|---|---|
| 50 mg | 0.5 mL | 50 units |
| 100 mg | 1 mL | 100 units |
Based on a 500 mg vial reconstituted with 5 mL of bacteriostatic water (100 mg/mL) and a U-100 insulin syringe. The dose amounts shown are commonly reported by the community and in anecdotal research, not recommendations or medical advice; only the reconstitution math (volume and units) is calculated for you.
How to calculate a NAD+ dose
- 1
Choose your vial and water
Select your NAD+ vial size (for example 500 mg) and the volume of bacteriostatic water you will add (for example 5 mL).
- 2
Find the concentration
Divide vial milligrams by water volume. 500 mg in 5 mL gives 100 mg/mL.
- 3
Calculate the draw
Divide your target dose by the concentration to get the volume in mL, then multiply by 100 to get units on a U-100 insulin syringe.
- 4
Verify on the syringe
Use the Keel calculator to see the exact draw rendered on a to-scale syringe, with a warning if the dose exceeds the syringe capacity.
NAD+ dosing FAQ
How do I reconstitute NAD+?
A common approach is to add 5 mL of bacteriostatic water to a 500 mg vial, which gives 100 mg/mL. Add the water slowly down the vial wall, swirl gently rather than shaking, and let the powder dissolve fully before drawing.
How many units is 50 mg of NAD+?
At 100 mg/mL, 50 mg equals 0.5 mL, which is 50 units on a U-100 insulin syringe.
What NAD+ doses do people report?
Community and anecdotal reports commonly cite 50 to 100 mg. These are figures people report, not a recommendation from Keel. NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular energy metabolism. It is studied for its potential roles in mitochondrial function, DNA repair, and healthy aging. Research doses are relatively large and are typically expressed in milligrams.
Which insulin syringe should I use for NAD+?
A U-100 insulin syringe is standard. A 0.3 mL (30-unit) syringe gives the most precise measurement for small draws, while a 0.5 mL or 1 mL syringe is better when the draw exceeds 30 units. Keel warns you when a dose is larger than the syringe you select.
How should I store NAD+ after reconstitution?
Reconstituted peptides are generally kept refrigerated and protected from light, with the unmixed powder stored cooler still. Follow the guidance from your supplier or a licensed healthcare professional for the specific compound.
What if my NAD+ dose is larger than the syringe holds?
Either use a larger insulin syringe or reconstitute with more bacteriostatic water to lower the concentration, which increases the volume per dose so it fits. Keel flags an over-draw and you can adjust the inputs until the draw fits.
Is NAD+ dosing the same for everyone?
No. The right draw depends on your vial size, how much bacteriostatic water you add, and your target dose. Always recalculate when any of those change, and consult a licensed healthcare professional.