Sermorelin Dosing Calculator & Reconstitution Guide
A growth hormone releasing hormone analog researched for GH support.
Sermorelin is a research peptide. A growth hormone releasing hormone analog researched for GH support. To dose it, reconstitute the vial (for example 5 mg in 2 mL of bacteriostatic water for 2.5 mg/mL), then divide your target dose by that concentration to find the units to draw.
- Category
- research peptide
- Dose unit
- mcg
- Commonly reported range
- 100-300 mcg
- Typical concentration
- 2.5 mg/mL
Use the Keel dose calculator to enter your numbers and see the exact units to draw, or use the built-in calculator further down this page.
What is Sermorelin?
Sermorelin is a growth hormone releasing hormone analog consisting of the first 29 amino acids of GHRH. It is studied for stimulating natural growth hormone production and is typically dosed in micrograms before bed. Also known as GRF 1-29.
How many units is each Sermorelin dose?
| Dose | Volume to draw | Units (U-100) |
|---|---|---|
| 100 mcg | 0.04 mL | 4 units |
| 200 mcg | 0.08 mL | 8 units |
| 300 mcg | 0.12 mL | 12 units |
Based on a 5 mg vial reconstituted with 2 mL of bacteriostatic water (2.5 mg/mL) and a U-100 insulin syringe. The dose amounts shown are commonly reported by the community and in anecdotal research, not recommendations or medical advice; only the reconstitution math (volume and units) is calculated for you.
How to calculate a Sermorelin dose
- 1
Choose your vial and water
Select your Sermorelin vial size (for example 5 mg) and the volume of bacteriostatic water you will add (for example 2 mL).
- 2
Find the concentration
Divide vial milligrams by water volume. 5 mg in 2 mL gives 2.5 mg/mL.
- 3
Calculate the draw
Divide your target dose by the concentration to get the volume in mL, then multiply by 100 to get units on a U-100 insulin syringe.
- 4
Verify on the syringe
Use the Keel calculator to see the exact draw rendered on a to-scale syringe, with a warning if the dose exceeds the syringe capacity.
Sermorelin dosing FAQ
How do I reconstitute Sermorelin?
A common approach is to add 2 mL of bacteriostatic water to a 5 mg vial, which gives 2.5 mg/mL. Add the water slowly down the vial wall, swirl gently rather than shaking, and let the powder dissolve fully before drawing.
How many units is 200 mcg of Sermorelin?
At 2.5 mg/mL, 200 mcg equals 0.08 mL, which is 8 units on a U-100 insulin syringe.
What Sermorelin doses do people report?
Community and anecdotal reports commonly cite 100 to 300 mcg. These are figures people report, not a recommendation from Keel. Sermorelin is a growth hormone releasing hormone analog consisting of the first 29 amino acids of GHRH. It is studied for stimulating natural growth hormone production and is typically dosed in micrograms before bed.
Which insulin syringe should I use for Sermorelin?
A U-100 insulin syringe is standard. A 0.3 mL (30-unit) syringe gives the most precise measurement for small draws, while a 0.5 mL or 1 mL syringe is better when the draw exceeds 30 units. Keel warns you when a dose is larger than the syringe you select.
How do I convert Sermorelin micrograms to insulin units?
Divide your dose in micrograms by the concentration in micrograms per millilitre to get the volume in millilitres, then multiply by 100 for units on a U-100 syringe. The Keel calculator does this for you and shows the draw on a to-scale syringe.
How should I store Sermorelin after reconstitution?
Reconstituted peptides are generally kept refrigerated and protected from light, with the unmixed powder stored cooler still. Follow the guidance from your supplier or a licensed healthcare professional for the specific compound.
What if my Sermorelin dose is larger than the syringe holds?
Either use a larger insulin syringe or reconstitute with more bacteriostatic water to lower the concentration, which increases the volume per dose so it fits. Keel flags an over-draw and you can adjust the inputs until the draw fits.
Is Sermorelin dosing the same for everyone?
No. The right draw depends on your vial size, how much bacteriostatic water you add, and your target dose. Always recalculate when any of those change, and consult a licensed healthcare professional.
Sermorelin side effects
See the adverse effects most commonly reported for Sermorelin and its class, and log your own experience over time, in the Peptide & GLP-1 Side Effects reference & tracker.